Scientific Programme

Scientific
Programme


02 NOVEMBER 2022 – WEDNESDAY
12.00Registration
HALL – A (This session will be in Turkish)
13.30-16.30Biyoteknolojik İlaçlarda Klinik Çalışmalar-Güvenlik Değerlendirmeleri
Safety Evaluations and Clinical Studies in Biotechnological Products
13.30-14.00Biyoteknolojik İlaçlar ve Üretim Süreçleri
Devrim Demir Dora
14.00-14.30Biyobenzer İlaçlarda Klinik Çalışmalar ve Karşılaştırılabilirlik
İrfan Çiçin
14.30-15.00Biyobenzer Ürünlerde Ekstrapolasyon, Değiştirilebilirlik
M.Cem Ar
15.00-15.30Biyoüstünler
Alper B. İskit
15.30-16.00Biyolojik ve Biyobenzer İlaçlarda Farmakovijilans, İzlenebilirlik ve Risk Yönetimi
Semra Şardaş
17.00-18.30Opening Ceremony
17.30-18.15Opening Lecture
The History of the Advancement of Toxicology in Turkey
Ali Esat Karakaya
18.00-20.00Opening Reception
20.00Dinner
03 NOVEMBER 2022 – THURSDAY
HALL – A
09.00-9.45Plenary Lecture
Non-Pharmacological Mechanism in Substance-Based Medical Devices/Challenges in Regulatory Definition
Marco Racchi
09.45-10.15Coffee Break
HALL – A, SESSION 1
10.15-12.15Genotoxic Impurities in Pharmaceutical Compounds
10.15-10.45Several years of experience with the use of the staged TTC concept (less than lifetime) for genotoxic impurities in drugs
Lutz Mueller
10.45-11.15Strategies on the assessment of genotoxic impurities in pharmaceuticals
Andreas Czich
11.15-11.45Regulation of Genotoxic Impurities – Guidelines and Experiences since 2006
Roland Froetschl
11.45-12.15Genotoxic impurities and other possible impurities in pharmaceutical products: From the application perspective
Ahmet Aydın
12.15-13.30Lunch
HALL – A
13.30-14.15Plenary Lecture
Chemical Stewardship through Sustainability Lenses
Salmaan H Inayat-Hussain
HALL – A, SESSION 2
14.30-17.00Vaccine Safety-Toxicity and Clinical Trials
14.30-15.00Vaccine Safety and Toxicity. What have We Learned from COVID-19 Pandemic
Pınar Erkekoğlu
15.00-15.30Clinical Trials of COVID-19 Vaccines
Serhat Ünal
15.30-16.00Vaccine Hesitancy
Levent Akın
16.00-16.30Pharmacoeconomic Aspects of COVID-19 Vaccines
Zafer Çalışkan
16.30-17.00Characterization and Quality Control Procedures for Vaccines: A Special Focus on COVID-19 Vaccines
Emirhan Nemutlu
HALL – B, SESSION 3
14.30-16.30Current approaches on detecting the DNA damage and repair of chemicals
14.30-15.00Genetic risks from heat-damaged DNA in food
Miral Dizdaroğlu
15.00-15.30Mode of action (MOA) based threshold for genotoxic carcinogens: Benzene case
Neslihan Aygün Kocabaş
15.30-16.00Mitochondrial DNA damage as genotoxicity marker
Nadja Cristhina de Souza Pinto
16.00-16.30Oligonucleotide Characterization for Emerging Modalities
Erdem Çoşkun
16.30-17.00The impacts of prominent detoxifying and repair gene polymorphisms on neurological diseases
Bensu Karahalil
17.00-17.15Coffee Break
HALL – A, SESSION 4
17.15-19.15Scientific Approach to Chemical Warfare and Fourth Generation Nerve Agents_Novichoks
17.15-17.45A generic presentation on fourth generation agents and their risks – novel therapeutic options for nerve agents/organophosphates poisoning
Ahmet Aydın
17.45-18.15Case studies for Novichok incidents in UK and Russia
Sermet Sezigen
18.15-18.45Review-based evaluation of decontamination techniques after Novichok exposure
Denis Josse (online)
18.45-19.15Chemical countermeasures: Future developments
Laura Cochrane
HALL – B, SESSION 5
17.15-19.15Environmental Biomonitoring of Hazardous Substances
17.15-17.45Air pollution context and biomonitoring in Sarajevo, Bosnia and Herzegovina
Anja Haveric
17.45-18.15Does Occupational Toxicology of Metals have any Future in Developed Countries?
Petar Bulat
18.15-18.45Tobacco biomonitoring (cotinine) in pregnant women and perinatal outcomes
Carla Costa
18.45-19.15Monitoring air pollution and the health-related biomarkers: lessons from HUMNap
Katarina Matkovic
20.00Dinner
04 NOVEMBER 2022 – FRIDAY
HALL – A
09.00-09.45Plenary Lecture
Safety Evaluation of Food Additives
Yalçın Duydu
09.45-10.00Coffee Break
HALL – A, SESSION 6
10.00-12.30Application of Comet Assay in Human Biomonitoring
10.00-10.30The comet assay in human biomonitoring: results from the COST Action hCOMET
Andrew Collins
10.30-11.00Standardization of comet assay in salivary leucocytes for human biomonitoring studies
Blanca Laffon
11.00-11.30Exposure to trihalomethanes in indoor swimming pools and DNA damage
Joao Paolo Texeira
11.30-12.00Effect of a meat-based diet on fecal water genotoxicity: a randomized clinical trial in healthy subjects
Lisa Giovannelli
12.00-12.30Different DNA damage levels assessed by the alkaline comet assay in Swiss albino mice after combine exposure to radiotherapeutic doses of ionizing radiation and different volatile anaesthetics
Mirta Milic
12.30-13.45Lunch
HALL – A, SESSION 7
13.45-15.45In Silico Toxicology
13.45-14.15Regulatory Applications of Computational Toxicology: Progress and Strategies to Ensure Wider Use
Kristie Sullivan
14.15-14.45In silico approaches to assess the potential environmental effects of diverse chemicals
Melek Türker Saçan
14.45-15.15Filling data gap for toxicological evaluation of pharmaceuticals: In Silico approach
Muhammed Hamitoğlu
15.15-15.45In silico toxicological evaluation of drug impurities aligned with ICH M7. A case study for methylprednisolone aceponate impurities
Gülçin Tuğcu
HALL – B, SESSION 8
13.45-15.45Current Concerns about Endocrine Disrupting Chemicals
13.45-14.15Causality Between Prenatal Exposure to Pharmaceuticals and Childhood Obesity
Hande Gürer Orhan
14.15-14.45Epigenetic Effects of Endocrine Disrupting Chemicals
Belma Koçer Gümüşel
14.45-15.15Zebrafish as a Model for Chemical Induced Adipogenesis and Related Metabolic Diseases
Jorke Kamstra
15.15-15.45Risk Assessment of Endocrine Disruptors
Johanna Zilliacus
15.45-16.00Coffee Break
HALL – A, SESSION 9
16.00-18.00Organ-specific Toxic Pathways: recent progress in drug-induced adversities
16.00-16.30Progress on mechanism of paracetamol-induced kidney damage
Hilmi Orhan
16.30-17.00Adverse outcome pathways for in vitro prediction of liver toxicity
Mathieu Vinken
17.00-17.30The role of mitochondria in cell death and regeneration during acetaminophen hepatotoxicity
Hartmut Jaeschke
17.30-18.00Increasing complexity of in vitro models for drug-induced nephrotoxicity enhances their predictive value
Roos Masereeuw
HALL – B, SESSION 10
16.00-18.00Conceptual models in immunotoxicology: alternative approaches and computational strategies
16.00-16.30Key characteristics of immunotoxicants: the way forward?
Dori E. Germolec
16.30-17.00In vitro tests addressing immunotoxicity with a focus on immunosuppression
Emanuela Corsini
17.00-17.30Integrated testing strategy for immunotoxicity
Marco Corvaro
17.30-18.00The Universal Immune System Simulator: an in silico model to predict the risk associated with exposure to immunotoxicants
Francesco Pappalardo
19.30 –Gala Dinner
05 NOVEMBER 2022 – SATURDAY
HALL – A
09.00-9.45Plenary Lecture
Mutidrug Resistance Protein-4 (Mrp4): A New Member in the Constellation of Factors Contributing to Non-alcoholic Liver Disease and Metabolic Syndrome
José E. Manautou
09.45-10.15Coffee Break
HALL – A, SESSION 11
10.15-12.15The safety of Nanomaterials
10.15-10.45Possible risks of interactions between nanometal mixtures and chemical contaminant in aquatic environment
Murat Özmen
10.45-11.15Effect of BaSO4 nanoparticles on human lung cells under different culture conditions
Heidi Foth
11.15-11.45Effects of Carbon Nanomaterials on environment
Bertrand Pourrut
11.45-12.15Genotoxicity of engineered nanomaterials: New approaches to hazard and risk assessment
Maria Dusinska
HALL – B, SESSION 12
10.15-12.15Lipids in health and diseases
10.15-10.45Mass Spectrometry Imaging of Cholesterol Metabolism in Brain
William Griffiths
10.45-11.15Sterol markers of cholesterol and bile acid metabolism
Dieter Luetjohann
11.15-11.45Attenuation of oxysterols-induced cytotoxicity by Lorenzo’s oil, a 4:1 mixture of oleic and erucic acid: potential benefits in age-related disease
Gerard Lizard
11.45-12.15Sphingolipid metabolism in toxicological exposures
Suna Sabuncuoglu
12.15Closing Remarks

11th International Congress of the Turkish Society of Toxicology


PCO

TUNGA TOUR DMC
Kemankeş Karamustafa Paşa Mah.
Gümüş Halka sk. No: 4 Kat: 2-3
34425 – Karaköy /Beyoğlu / Istanbul
ttd2022@tungatour.com
registration@tungatour.com
+90 212 243 22 40
+90 532 762 75 95

Secretariat

Assoc. Prof. Dr. Özlem ATLI EKLİOĞLU
Anadolu University, Faculty of Pharmacy
Department of Toxicology
26210 Tepebaşı/Eskişehir/Turkey
ttdkongre2022@gmail.com
+90 (222) 335 0580 / 3755

Tunga Tour, 2021