Scientific Programme

Scientific
Programme


02 NOVEMBER 2022 – WEDNESDAY
12.00Registration
HALL – A (This session will be in Turkish)
13.30-16.30Biyoteknolojik İlaçlarda Klinik Çalışmalar-Güvenlik Değerlendirmeleri
Safety Evaluations and Clinical Studies in Biotechnological Products
Biyoteknolojik İlaçlar ve Üretim Süreçleri
Devrim Demir Dora
Biyobenzer İlaçlarda Klinik Çalışmalar ve Karşılaştırılabilirlik
İrfan Çiçin
Biyobenzer Ürünlerde Ekstrapolasyon, Değiştirilebilirlik
M.Cem Ar
Biyoüstünler
Alper B. İskit
Biyolojik ve Biyobenzer İlaçlarda Farmakovijilans, İzlenebilirlik ve Risk Yönetimi
Semra Şardaş
17.00-18.30Opening Ceremony
17.30-18.15Opening Lecture
The history of the advancement of toxicology in Turkey
Ali Esat Karakaya
18.00-20.00Opening Reception
20.00Dinner
03 NOVEMBER 2022 – THURSDAY
HALL – A
9.00-9.45Plenary Lecture
Safety evaluation of pharmaceuticals and medical products
Mary Ellen Cosenza
9.45-10.15Coffee Break
HALL – A, SESSION 1
10.15-12.15Genotoxic Impurities in Pharmaceutical Compounds
10.15-10.45Several years of experience with the use of the staged TTC concept (less than lifetime) for genotoxic impurities in drugs
Lutz Mueller
10.45-11.15Strategies on the assessment of genotoxic impurities in pharmaceuticals
Andreas Czich
11.15-11.45Regulation of Genotoxic Impurities – Guidelines and Experiences since 2006
Roland Froetschl
11.45-12.15Genotoxic impurities and other possible impurities in pharmaceutical products: From the application perspective
Ahmet Aydın
12.15-13.30Lunch
HALL – A
13.30-14.15Plenary Lecture
Environmental pollutants and severity of COVID-19 and other infections by respiratory virus
Jose L. Domingo
14.15-14.30Coffee Break
HALL – A, SESSION 2
14.30-16.45Vaccine Safety-Toxicity and Clinical Trials
Vaccine Safety and Toxicity. What have We Learned from COVID-19 Pandemic
Pınar Erkekoğlu
Clinical Trials of COVID-19 Vaccines
Serhat Ünal
Vaccine Hesitancy
Levent Akın
Pharmacoeconomic Aspects of COVID-19 Vaccines
Zafer Çalışkan
Characterization and Quality Control Procedures for Vaccines: A Special Focus on COVID-19 Vaccines
Emirhan Nemutlu
HALL – B, SESSION 3
14.30-16.45Scientific Approach to Chemical Warfare and Fourth Generation Nerve Agents_ Novichoks
A generic presentation on fourth generation agents and their risks – novel therapeutic options for nerve agents/organophosphates poisoning
Valentine Nzenzung
Case studies for Novichok incidents in UK
Paul Russell
Navalyn incident and verification of nerve agent exposure including Novichok in human samples
Sermet Sezigen
Review-based evaluation of decontamination techniques after Novichok exposure
Denis Josse
Chemical countermeasures: Future developments
Laura Cochrane
16.45-17.00Coffee Break
HALL – A, SESSION 4
17.00-19.00Current approaches on detecting the DNA damage and repair of chemicals
Mode of action (MOA) based threshold for genotoxic carcinogens: Benzene case
Neslihan Aygün Kocabaş
Mitochondrial DNA damage as genotoxicity marker
Nadja Cristhina de Souza Pinto
Oligonucleotide Characterization for Emerging Modalities
Erdem Çoşkun
The impacts of prominent detoxifying and repair gene polymorphisms on neurological diseases
Bensu Karahalil
Genetic risks from heat-damaged DNA in food
Miral Dizdaroğlu
HALL – B, SESSION 5
17.00-19.00Environmental Biomonitoring of Hazardous Substances
Air pollution context and biomonitoring in Sarajevo, Bosnia and Herzegovina
Anja Haveric
Does Occupational Toxicology of Metals have any Future in Developed Countries?
Petar Bulat
Monitoring air pollution and the health-related biomarkers: lessons from HUMNap
Marco Geric
Tobacco biomonitoring (cotinine) in pregnant women and perinatal outcomes
Carla Costa
….TBA…..
Mykola Prodanchuk
20.00Dinner
04 NOVEMBER 2022 – FRIDAY
HALL – A
9.00-9.45Plenary Lecture
Safety Evaluation of Food Additives
Yalçın Duydu
9.45-10.15Coffee Break
HALL – A, SESSION 6
10.15-12.15The Safety of Nanomaterials
Possible risks of interactions between nanometal mixtures and chemical contaminant in aquatic environment
Murat Özmen
Effect of BaSO4 nanoparticles on human lung cells under different culture conditions
Heidi Foth
Effects of Carbon Nanomaterials on environment
Bertrand Pourrut
Genotoxicity of engineered nanomaterials: New approaches to hazard and risk assessment
Maria Dusinska
12.15-13.30Lunch
HALL – A, SESSION 7
13.30-15.30In Silico Toxicology
Regulatory Applications of Computational Toxicology: Progress and Strategies to Ensure Wider Use
Kristie Sullivan
In silico approaches to assess the potential environmental effects of diverse chemicals
Melek Türker Saçan
Filling data gap for toxicological evaluation of pharmaceuticals: In Silico approach
Muhammed Hamitoğlu
In silico toxicological evaluation of drug impurities aligned with ICH M7. A case study for methylprednisolone aceponate impurities
Gülçin Tuğcu
HALL – B, SESSION 8
13.30-15.45Application of Comet Assay in Human Biomonitoring
The comet assay in human biomonitoring: results from the COST Action hCOMET
Andrew Collins
Standardization of comet assay in salivary leucocytes for human biomonitoring studies
Blanca Laffon
Exposure to trihalomethanes in indoor swimming pools and DNA damage
Joao Paolo Texeira
Effect of a meat-based diet on fecal water genotoxicity: a randomized clinical trial in healthy subjects
Lisa Giovannelli
Different DNA damage levels assessed by the alkaline comet assay in Swiss albino mice after combine exposure to radiotherapeutic doses of ionizing radiation and different volatile anaesthetics
Mirta Milic
15.45-16.00Coffee Break
HALL – A, SESSION 9
16.00-18.00Organ-specific Toxic Pathways: recent progress in drug-induced adversities
Progress on mechanism of paracetamol-induced kidney damage
Hilmi Orhan
Adverse outcome pathways for in vitro prediction of liver toxicity
Mathieu Vinken
The role of mitochondria in cell death and regeneration during acetaminophen hepatotoxicity
Hartmut Jaeschke
Increasing complexity of in vitro models for drug-induced nephrotoxicity enhances their predictive value
Roos Masereeuw
HALL – B, SESSION 10
16.00-18.00Lipids in Health and Diseases
Mass Spectrometry Imaging of Cholesterol Metabolism in Brain
William Griffiths
Sterol markers of cholesterol and bile acid metabolism
Dieter Luetjohann
Attenuation of oxysterols-induced cytotoxicity by Lorenzo’s oil, a 4:1 mixture of oleic and erucic acid: potential benefits in age-related disease
Gerard Lizard
Sphingolipid metabolism in toxicological exposures
Suna Sabuncuoglu
19.30 –Gala Dinner
05 NOVEMBER 2022 – SATURDAY
HALL – A
9.00-9.45Plenary Lecture
Mutidrug Resistance Protein-4 (Mrp4): A New Member in the Constellation of Factors Contributing to Non-alcoholic Liver Disease and Metabolic Syndrome
José E. Manautou
9.45-10.15Coffee Break
HALL – A, SESSION 11
10.15-12.15Current Concerns about Endocrine Disrupting Chemicals
Causality Between Prenatal Exposure to Pharmaceuticals and Childhood Obesity
Hande Gürer Orhan
Epigenetic Effects of Endocrine Disrupting Chemicals
Belma Koçer Gümüşel
Zebrafish as a Model for Chemical Induced Adipogenesis and Related Metabolic Diseases
Jorke Kamstra
Risk Assessment of Endocrine Disruptors
Johanna Zilliacus
HALL – B, SESSION 12
10.15-12.15Conceptual Models in Immunotoxicology: alternative approaches and computational strategies
Key characteristics of immunotoxicants: the way forward?
Dori E. Germolec
In vitro tests addressing immunotoxicity with a focus on immunosuppression
Emanuela Corsini
Integrated testing strategy for immunotoxicity
Marco Corvaro
The Universal Immune System Simulator: an in silico model to predict the risk associated with exposure to immunotoxicants
Francesco Pappalardo
12.15Closing Remarks

11th International Congress of the Turkish Society of Toxicology


PCO

TUNGA TOUR DMC
Kemankeş Karamustafa Paşa Mah.
Gümüş Halka sk. No: 4 Kat: 2-3
34425 – Karaköy /Beyoğlu / Istanbul
ttd2022@tungatour.com
registration@tungatour.com
+90 212 243 22 40
+90 532 762 75 95

Secretariat

Assoc. Prof. Dr. Özlem ATLI EKLİOĞLU
Anadolu University, Faculty of Pharmacy
Department of Toxicology
26210 Tepebaşı/Eskişehir/Turkey
ttdkongre2022@gmail.com
+90 (222) 335 0580 / 3755

Tunga Tour, 2021